Web1 day ago · Herein, a feasible strategy to enhance the water solubility of potential anti-tumor drugs was utilized, which was to combine hydrochloric acid or sulf… WebMar 3, 2024 · The high variability of curcumin preparations and sources makes static RC an important factor of variability and can lead to unpredictable or potentially …
Curcumin: Biological, Pharmaceutical, Nutraceutical, and …
Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cosmetics ingredient, food flavoring, and food coloring. Chemically, curcumin is a … See more Curcumin was named in 1815 when Henri Auguste Vogel and Pierre Joseph Pelletier reported the first isolation of a "yellow coloring-matter" from the rhizomes of turmeric. Later, it was found to be a mixture of See more Curcumin, which shows positive results in most drug discovery assays, is regarded as a false lead that medicinal chemists include among "pan-assay interference compounds". … See more As a component of turmeric, curcumin may interact with prescription drugs and dietary supplements. In high amounts, it may be unsafe for women during pregnancy. It may … See more Though there is no evidence for the safety or efficacy of using curcumin as a therapy, some alternative medicine practitioners give it intravenously, supposedly as a treatment for numerous … See more The most common applications are as an ingredient in dietary supplement, in cosmetics, as flavoring for foods, such as turmeric-flavored … See more Curcumin incorporates a seven carbon linker and three major functional groups: an α,β-unsaturated β-diketone moiety and an aromatic O-methoxy-phenolic group. The aromatic ring systems, which are phenols, are connected by two α,β-unsaturated See more Although curcumin has been assessed in numerous laboratory and clinical studies, it has no medical uses established by well-designed clinical research. According to a 2024 review of … See more earthworm jim genesis rom
Hybrid Curcumin Compounds: A New Strategy for Cancer Treatment
WebApr 11, 2024 · Curcumin is a hydrophobic compound that requires a suitable carrier to enhance its solubility and stability. The use of γ-CD-MOFs as a carrier for curcumin can prevent its premature degradation and loss of activity. In addition, the preservation mechanism of the curcumin-loaded γ-CD-MOF-based biological packaging film has not … WebDec 12, 2014 · Mother Nature is a huge source of natural compounds providing scaffolds that can be combined, such that potent hybrids emerge as a novel drug discovery approach. ... Priyadarsini, K.I. Chemical and structural features influencing the biological activity of curcumin. Curr. Pharm. Des. 2013, 19, 2093–2100. [Google Scholar] WebPlant-derived natural products are an ideal source of such therapies due to their diversity and capacity to target multiple growth pathways in cancer. ... -1,6-heptadiene-3,5-dione; Figure 1). 41,43 Researchers found that curcumin has many biological activities due to the huge chemical diversity of its metabolites. 44 The most important ... earthworm jim genesis ost