WebApr 10, 2024 · Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity Ototoxic side effects of cisplatin and aminoglycosides have been extensively studied, but no therapy is available to date. Sensory hair cells, upon exposure to cisplatin or aminoglycosides, undergo apoptotic and necrotic cell death. WebAbstract Cisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. ... adenocarcinoma promotes proliferation via the accumulation of β-catenin 17 and regulates lung tumorigenesis through cell apoptosis and autophagy pathways. 16 USP14 is critical ...
Cisplatin nephrotoxicity: new insights and therapeutic …
WebIt has been reported that cisplatin upregulates the expression levels of Trail, initiator caspase 8, and effector caspase 3, leading to apoptosis in hES [14]. The upregulation of p53, caspase... WebSynergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis Synergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis Authors Min Liu 1 , Shumei Ma 2 , Mingbo Liu 2 , Yufei Hou 2 , Bing Liang 2 , Xu Su 3 , Xiaodong Liu 4 Affiliations birds of prey streaming vf free
Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to
WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 … WebOct 16, 2006 · Cisplatin is a broad-spectrum anticancer drug that is also widely used in experimental studies on DNA damage-induced apoptosis. Induction of apoptosis within … WebLTTs minimise cisplatin-induced DNA damage and evade apoptosis by increased expression of anti-apoptotic factors. The observed diversity among the four LTTs highlights the complexity of cisplatin resistance mechanisms even within one tumour entity, explaining heterogeneity in patient responses to chemotherapy. birds of prey stream complet vf streaming